Can anyone tell me whether Cervarix - the GlaxoSmithKline HPV vaccine the Scottish government is poised to give to all girls aged between 12 and 17 - differs in any significant ways from Merck's Gardasil, about which WDDTY has been cautioning for some time? Specifically, does it have a comparable safety record, a better one or a poorer one?

There is a major advertising campaign (the website has the emotive URL fightcervicalcancer.org.uk) now under way across Scotland and when the schools go back in 10 days' time, the pressure will be piled on eligible girls to take part. (The programme is school-based.) I am encouraging my 16-year-old daughter to research the matter very thoroughly before committing and am instinctively against her having these jabs (she's not had MMR or MenC), but at the same time I feel that I should allow her to make her own decision based on all the available information.What I need, though, is a lot more information, so all help greatly appreciated!

Thanks

Both vaccines are for prevention from certain sexually transmitted strains of human papillomavirus (HPV) associated with the development of cervical cancer and genital warts. Of the more than 100 known HPV types, 37 are known to be transmitted through sexual contact. Some types of HPV, particularly type 16, have been found to be associated with oropharyngeal squamous-cell carcinoma, a form of throat cancer. HPV types 6 and 11 cause about 90% of genital wart cases.

While Cevarix shots can block infections from HPV types 16, 18, 31 and 45, Gardasil – from HPV types 6, 11, 16 and 18. Both vaccines contain L1 protein of the viral capsid – it is hollow protein shell of the virus which mimics the viral particles in the body and tricks immune system to mount immune response and to produce specific antibodies against real virus once the body is exposed to that. As a bioscientist I can assure you that both vaccines DO NOT contain live virus (nothing like Biavax II -Rubella and Mumps Live Virus Vaccine) because L1 protein shell does not have any genetic material (DNA) inside therefore can not be infectious because no one virus can replicate if DNA or RNA is missing within the shell (as far as science concerns, this is the property of prions only).

In both vaccines L1 protein was produced using recombinant technology when DNA bit containing required for L1 synthesis gene (so called ‘vector’) is inserted into a carrier system so called 'expression system' (often rapidly replicating therefore cost-effective bacterial cells system) . The carrier system cells perform transcription and translation of the genes including the one that produces L1 protein. This protein is then isolated, purified and then becomes a constituent of a branded formulation. The vector construction and a carrier system for each protein can be subject to patenting.

I believe there was a problem with Gardasil’s L1 protein folding at early stages of development (when misfolded, the protein can acquire the wrong 3-D conformation therefore can lose its expected properties), but this was resolved later.

Anyone who is sexually active can get HPV and genital warts. Both men and women can be carriers of HPV. Clinical trial on comparison of both vaccines effectiveness is still carried on.

Phase II trials demonstrated 100% protection of Cervarix vaccine against types 16 and 18 HPV. Although Gardasil provides protection against HPV 11 and 6 in addition to 16 and 18, Cervarix was chosen for national programme of vaccination for teenage girls over Gardasil presumably for cost reasons.

Anyway, to my opinion ‘a bird in the hand is worth two in the bush’.

 Hope it helps.

---

Alla Cranham, MSc ABMT,
Registered Homotoxicologist

Mercury House
Northgate
Nottingham
NG7 7FN

Tel +44(0) 845 450 7316
Mob +44(0) 77361 47458
Fax +44(0) 115 9163109
http://www.in-vivo-health.co.uk

Cervarix sounds like just another attempt by the powers that be to poison our children, aka the future adults,by producing vaccines for "hyped up"  or should that be MARKETED illnesses and diseases which in reality pose a TINY risk to us.

In my opinion there are NO safe vaccines.

Your daughter should Google Dr.Sherri Tenpenny or search on You Tube for her videos about vaccines...

Most kids today are subjected to about 20 vaccines...what the hell...one more won't hurt...or will it?

www.infowars.com

www.davidicke.com

The above websites contain info which states that there is a global attempt to reduce the world population by as much as 80%.

AIDS...vaccines...avian flu...certain food additives like aspartame...are some of the ways this is being carried out.

IVF is massive today because the side effects of some of these chemicals,along with other factors,is INFERTILITY.

Alex Jones on www.infowars.com talks about instances where manufacturers have PURPOSELY put the aids virus in vaccines!!!!

In the 1980's drug company BAYER sold an AIDS tainted blood clotting drug to Latin Americ,Asia and Europe...they knew it was tainted but had to get rid of their stock and even continued to produce it AFTER they were forced to pull it off the market!!!...see www.mercola.com for this story.

Visit www.healthfreedomusa.org ...a great info source...and you can read  Dr.Rima Laibow  talk about how the flu vaccine FLUMIST is actually designed to SPREAD avian flu and create a pandemic.

On a more sinister note...since about the mid 1990's,microchips have been small enough to be inserted into humans during vaccination programs...

The bottom line is this...The Government and health "authorities" DO NOT have your GOOD health at heart...

Many people will dismiss the above as "conspiracy nonsense"...I can hear Harradine firing up his computer now...but it is really just information for you and your daughter to use to make more accurate decisions about the your most valuable assest...your health.

Hope it helps.

 

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Robin Allan
Chek Practitioner
Natural Health Coach

http://www.robinallan.com


robin_allan@hotmail.com

07967-366470

Looks as though you have been reading the same information as me blobby.  Anyone who doesn't believe in a conspiracy by Big Pharma is seriously out of touch with reality.  Websites and networks are operating all over the world now exposing the truth about vaccines and anyone can find out about them if they really want to.  The trouble is, most do not want to know the truth because it is too hard to accept that we have been so brainwashed for so long.   New York Post revealed on 6th July that Gardasil was under investigation for possible links to paralysis, seizures and 18 deaths.  CDC and FDA knew about the link between vaccines and Autism in 2000. A great new website on vaccines is www.veirascheibner.org. We have been misinformed that the vaccines cured many diseases, but they have created new sicknesses and compromised the immune system of generations of children.  The $billions spent on vaccines should be diverted to holistic cures and preventative medicine.  Check out a woman called Eleanor McBean who witnessed the 1918 Flu Pandemic as an unvaccinated and healthy child.

 

Looks like homeopathy should be banned just as well if everyone is to acquire this attitude as homeopathic nosodes act as micro-vaccinations stimulating immune system to produce specific antibodies. By the way, non-specific antibodies also help to fight invaders as antibodies are capable to cross-reacting with non-specific antigens due to very reactive paratopic ends. May be reading a little bit of basic immunology textbooks will help? 

Unfortunately we do not live in sterile world, and I can't see anything wrong with preparing immune system for possible invaders at the right time, i.e. when immune system is not compromised with any other antigens. Cases of adverse reactions to vaccinations and their side effects are only due to lack of diagnostic information on particular patient at the time of vaccination. May be this side of healthcare needs to be tackled first? There are plenty of cost-effective and non-invasive devices for health assessment based on biophysical methods and/or computational analysis available in private healthcare, but conventional medicine mainly accepts biochemical approach to life based on routine 'wet analysis' of bodily fluids. Well, someone said that the strongest instinct of human beings is not self-preservation, but conservatism.

---

Alla Cranham, MSc ABMT,
Registered Homotoxicologist

Mercury House
Northgate
Nottingham
NG7 7FN

Tel +44(0) 845 450 7316
Mob +44(0) 77361 47458
Fax +44(0) 115 9163109
http://www.in-vivo-health.co.uk

Many thanks - much appreciated. I would, though, be grateful if you could answer a few more Qs, or point me in the right direction if you can't:

1. You say that "some types" of the HPV virus, particularly 16, are associated with a type of throat cancer and that 6 and 11 cause the majority of genital warts. Can you tell me how many of all the 100-plus HPV types have been directly linked to cervical cancer? Of these, how many of the 37 sexually-transmitted versions have been directly linked to cervical cancer?
   
2. If Cervarix only protects against four types and Gardasil four types (both covering 16 and 18), what is the estimated likelihood of a vaccinated child or woman contracting cervical cancer from any of the remaining 90-plus types?
3. Can you give any scientifically-based explanation of why GSK chose to offer protection against types 16, 18, 31, and 45 while Merck went for 6, 11, 16,and 18?
   
4. You say that the Phase II trials show Cervarix offers 100 per cent protection against 16 and 18. Can you say for how long the programme of jabs planned by the Scottish government provides this 100 per cent protection? 
5. Can you explain in laymen's terms exactly why the FDA has yet to licence Cervarix? I believe it's to do with one of the ingredients?
   
6. In your second post, you say that "cases of adverse reactions to vaccinations and their side effects are only due to lack of diagnostic information on particular patient at the time of vaccination". Does this mean that no vaccines cause any standalone adverse reactions and that any reactions that do occur are the consequences solely of undiagnosed conditions?
   
7. Finally, have you any idea why are only girls and women being targeted with this vaccine given that men are also carriers and transmitters of HPV?
   

Many thanks.

 

 

I do not think these questions should be addressed to the WDDTY community members to be answered. I am certainly not in the position to answer all your questions as I never participated in these vaccines development. I was trying to explain to you the basics of science behind vaccine constituents which are relevant to my scientific background.

I certainly can not say why GSK’s choice differs from Merk’s, and the choice may not have been governed by scientific reason…  Why not email your questions to GSK’s customer desk? I believe detailed information on Cervarix is available from the European Medicines Agency (EMEA) web site: http://www.emea.europa.eu/.

 

To my opinion, healthy immune system is capable producing healthy immune response to any antigen introduced in moderate amounts: raise antibodies and eliminate these antigens. With aging we get more exposed to different antigens exhausting our immune system to the point when it starts making mistakes.

I think that such specific questions should be addressed appropriately to those who are entitled to answer them - not to me, I am afraid.

Sorry.

---

Alla Cranham, MSc ABMT,
Registered Homotoxicologist

Mercury House
Northgate
Nottingham
NG7 7FN

Tel +44(0) 845 450 7316
Mob +44(0) 77361 47458
Fax +44(0) 115 9163109
http://www.in-vivo-health.co.uk

OK, Alla - thanks. I'll try contacting GSK and Merck and see what they say.

Could you, though, answer my question about adverse reactions as that's generic rather than specific and I'm keen to find out more about this as it's really hard to get past the hype coming from both the pro- and anti-vaccine camps.

Thanks again.

 

In the USA boys ARE on the verge of being vaccinated with Gardasil...see www.mercola.com for more info on this.

---

Robin Allan
Chek Practitioner
Natural Health Coach

http://www.robinallan.com


robin_allan@hotmail.com

07967-366470

Don't bank on getting much out of GSK though they did admit over the phone to my GP nurse that. the mercury in vaccines could have been harmful to me. I believe it was the 3 Hep B vaccines I have when I was nursing in 1990 that was a trigger for my chronic fatigue and fibromyalgia.

Have a look at this.

http://www.ageofautism.com/2008/06/two-more-deaths.html

Also GMTV jabs forum is a good site for learning pros & cons of vaccines.

Personally I am not in favour of the Gardasil mainly from an ethical point of view & think it will encourage promiscuity even more giving girls a false sense of security.

Adrienne.

 

I searched the web for vaccination related material by Dr Sherri Tenpenny. I have to say that what I could find sounds more like politician’s pitch rather than scientifically justified facts, although there is an indication of more detailed information available from her DVD and book, but these have to be purchased first. If this information is so valuable, well referenced and life saving – why not make it available to everyone free of charge? To me it looks more like implication of a marketing plan.

Certainly the statement that “Vaccines are grown on and contain foreign tissue and altered genetic material of both human and animal origin” does not make any scientific sense to me.

I agree that vaccines may produce side effects as any pharmaceutical drug can. But when considering health or disease we have to evaluate all possible risks against possible benefits.  

Thiomersol is no longer used in single-dose vaccine formulations, but controversy is still there. We are subjected in every day life to loads of harmful chemicals not only in drugs and vaccines, but also in our food, water, soil, air etc. Some of them are so called endocrine disruptors, and endocrine system is integral part of PNIE (Psycho Neuro Immuno Endocrine) system. According to Prof. Kirkman, the whole planet suffers from Universal Immune Compromisation Syndrome (UICS). The whole issue is in quantification as these harmful substances may be accumulating in the body or might be eliminating from the body. How to find out what’s happening there and to what extend?

Besides that we are also subjected to loads of invisible invaders such as bacteria, protozoa, viruses…you name it! If immune system is not prepared for such intervention, once in the body, the viruses tend to undertake either lytic or lysogenic life cycle. Lytic cycle means disease development; lysogenic cycle means that the virus has built its genetic material into its host cell genome and will stay latently until such time when the host cell suffers from glucose deprivation and immune system is down. Administration of any vaccine will certainly challenge immune system, and if immune system is down at the time or not very strong due to genetic factors influence, the dormant viruses may be re-activated in the body. To my opinion, cytomegalovirus (CMV) is the most vicious in terms of the vaccination risk possession. You may wish to try asking your GP if your daughter could be tested for CMV DNA by PCR method prior to vaccination with Cervarix. I would be very interested to hear what would they say.

Good luck.

---

Alla Cranham, MSc ABMT,
Registered Homotoxicologist

Mercury House
Northgate
Nottingham
NG7 7FN

Tel +44(0) 845 450 7316
Mob +44(0) 77361 47458
Fax +44(0) 115 9163109
http://www.in-vivo-health.co.uk

Blobby, whilst I am as suspicious as you of big pharma, big chemical, big food etc., there are a lot of scare-mongering conspiracy theories flying around on the internet.  I would not believe most of it.  What happens in the world is generally driven by big bucks, not killing us off.  If they kill us off, they do not have anyone to make big bucks out of.

About the subject matter, I would not intend to permit my daughter to be vaccinated against HPV. It would be better to teach her about the virus, promiscuity, and safe sexual practise etc.  Vaginal pH balance is very important for good health in this department.  This can be accomplished by a low sugar, well balanced whole food diet, NO SMOKING (also linked to cervical cancer), a good daily vit/mineral supplement and pro-biotics supplements to provide immune boost and friendly bacteria.  

 

Mandy Lock, Chiropractor

Mandy,

There is a level of this that is way above the mere aquisition of money...ultimately it is about power and control of the world population.

It is about money at the level that interacts with us directly...drug companies,politicians,military etc but it is the opportunity to make billions that is the motivating force for these organisations to further an agenda that most of them are not even aware exists...they are being scammed just like we are.

The people who orchestrate this have no need of money...they are already richer than God!!

It has been designed as such that we should just see it as all being about money...that way we don't try to see past it at the real agenda.

There are indeed many barmy conspiracy theories out there and you have to be vigilant in what you read and believe.

www.davidicke.com  Highly recommended...Disregard the media crap about Icke...make your own mind up.

www.infowars.com  Texan Alex Jones...he can be a bit over the top but the info is sound.

Blobby

 

---

Robin Allan
Chek Practitioner
Natural Health Coach

http://www.robinallan.com


robin_allan@hotmail.com

07967-366470

Thanks Alla - all much appreciated, and thanks to everyone else for their input.

I think I can confidently guess what my GP would say if I asked for a test to see whether my daughter is a CMV carrier but I may well give it a try! Since statistically there's a 50%+ chance that she is, and with the greatest respect to Alla, I'll add that to my list of contraindications for this vaccine.

I have to say that I'm becoming increasingly alarmed by what I've found out about Gardasil, and the lack of independent information about Cervarix only makes me more uneasy. So far nothing I've read has given me a cogent and compelling argument in support of the principle of the vaccine and Gardasil's track record thus far in the US is hardly reassuring. Still to tackle GSK, but I'd be surprised if I get back anything other than a good PR pitch.

At the heart of all arguments in favour of vaccination programmes - and I am prepared to be convinced by some of them - is the herd immunity proposition, that individual adverse affects can be justified in the context of serving the greater good through mass protection against infectious disease epidemics. However, unless I'm really missing something crucial, this argument appears to be absent here. The jab is being directly "sold" - in Scotland anyway - as protection against cervical cancer (which in itself it isn't, of course) and as far as I'm aware cancer is not an infectious disease. HPV is infectious but not in itself greatly compromising; it can be a trigger (as can, say, smoking) rather than a direct cause of cervical cancer. (If I'm wrong, please someone correct me.) So the vaccine protects against some strains of a virus which can be involved in the development of cancer. Where's the herd immunity argument here? Wiping out these targetted strains (which is presumably the long-term aim) will not rid the world of HPV or cervical cancer - or, again, have I missed something? And anyway what about all the rest of the strains? More vaccines, some time in the future? And then a few more? And are boys and young men going to be vaccinated as well? (I know this was mooted in some states in the US but it seems to have drifted off the agenda again.)

I am also unclear about how long Gardasil or Cervarix are supposed to protect for - suppose, like MMR, it becomes clear their lifespan is limited. And if it were limited to, say, five or six years, where does that leave the 10-year-old girls being vaccinated with Cervarix in the coming year?

No, I'm not convinced by anything I've read so far. This is in no way to diminish the consequences of being diagnosed with cervical cancer: I have had treatment for pre-cancerous cervical cells myself and so have some very small inkling of the trauma involved. But, as I've said, nothing I've found so far convinces me that these vaccines are the right direction for our, or any other, government to be taking and the money involved could be spent much more wisely. I'm not by nature a conspiracy theorist, but it does seem so blatantly obvious that it's Merck and GSK who stand to gain the most here.

I withstood considerable pressure (some of it verging on emotional blackmail) from the medical profession when I opted against my daughter having MMR and later MenC; what's different this time is that she is now 16 and by law it's her decision, not mine. It's her, not me, who will be subject to the full force of the pressure (with additional peer pressure) as this programme is being adminstered through Scottish schools. At the moment's she's undecided. She's a feisty girl and she's very good at weighing up arguments, so we'll see.

I will keep you posted!

emv

 

 

Just unearthed something a bit scary in the EMEA report licensing Cervarix for use across the EU: "This application concerns the first vaccine for human use that has been produced with a Baculovirus Expression Vector System." Alla explained the mechanics of this bit of what appears to me as a lay person to be genetic engineering, but I didn't realise it was brand new technology. Has it popped up anywhere else, does anyone know?

This must be what's led the FDA to ask for more evidence to support the US application.