I don't know what to make of this article.  It reports that a number of drug trials were stopped early after limited testing on a small number of patients due to premature conclusions about the drugs' effectiveness.  The article doesn't state how effective the drugs turned out to be.  If in fact the drugs were effective on patients from the population at large without unsuspected serious side effects, the judgment of the researchers and regulators was vindicated, so there should be no complaint.

My personal view is that, if there is a reasonable alternative for treatment, don't use a new drug, regardless of the adequacy of its trial.  Wait reports of side effects until the drug has been on the market for five years or so.